We have superchargers in Indiana on all the major routes. No need to be uncomfortable. The biggest issue you'll face here is the average speed is 80+ mph which hurts efficiency.
Sasha also makes me ride in the car with the windows up and no AC in the summer, so I think it is not a matter of superchargers, but his own obsession with efficiency. We made the trip from Indianapolis to Toronto with only 2 supercharger stops, it was very cool.