So basically, it is not possible to drain 12V battery, as long as the main battery is in a healthy state of charge?
That’s correct. The 12 Volt battery drops to a certain level and then is recharged.
There’s a long thread in the S forums about trickle chargers to sustain 12 Volt battery at optimum charge level when car is parked at home.
Also, be careful if you connect a cable to tap the car’s 12 Volt system. The system tracks power used to charge the 12 Volt battery vs. power pulled by the 12 Volt circuits. If you connect to the battery and pull significant power, there will be a discrepancy.
It will look like the 12 Volt battery has internal short and is degrading. Soon the car will alert to replace the battery.
If you attach to the power distribution block, the drain is metered. No discrepancy, no false alerts.
Learned the above while figuring out how to connect a high-capacity AC inverter in our S. Son-in-law had plans to run two sous vide cookers for a high-visibility tailgate party.