I've done it through both the 18 at waterman and the 330. One time the 330 was closed so had to take the 18. Both routes are similar I believe but think the 330 is the best route. Plus there is a super charger in Fontana that you can quickly charge for a short amount of time if you are worried about it.
I guess I'd disagree about 330 being the best route though...
Too much traffic... Roadway full of buses and Honda civics with bald tires, constant rock dangers.
A guy in an BMW m3 with traction cables blew by me shortly after the chain checkpoint on 330.
Half hour later I found a piece of his traction cable with one of my tires.
There was no safe place to swap into the spare. With all the snow and ice on the ground, and we were in an area with no cell reception and since it was the rear tire I kept the truck in 4 HI, and crawled along on the flat tire for about 9 or 10 miles until I came up to that one country store.
When we got there we were able to have a tow truck come and swap me into my full-size spare.
(I only had a bottle jack and in a silverado 4x4 the bottle jack is incredibly dangerous and unstable...)
The way I know the road debris belonged to the BMW driver?
About 5 miles up we encountered a bit of traffic. Saw the M3 smashed up and being loaded onto a flatbed. Chains somewhat attached to what was left of his tires and rims...
Karma is a bitch.