The final cut of TMC Podcast #34 is available now with topics timestamped. We covered Tesla's rollercoaster prices, Toyota pushing junk science, Mike's new Model 3, Optimizing track mode for snow driving, FSD V11 apparently coming by the end of this week, and more. You can watch and check out the chat replay on YouTube.
I can't say I have done that, however you have to keep in mind the main battery pack is a huge amount of capacity. A freezer probably uses no more than 100W (and probably a lot less on average), so you might lose a couple miles if you left it running all day.
Note that most (?) 12V coolers run on the principle of the Peltier effect. One side of the electrical junction (basically a metal plate) gets cold while the opposite side gets hot. That heat has to go somewhere and usually means the surrounding area of the cooler will get warm. If it's run inside the cabin while driving, you may have to compensate with a lower temperature on you A/C.