I completed a Philadelphia to Colorado run about 10 days ago, including a stretch of 95 down to Fredericksburg. Some observations:
1. Rest stop bathrooms are mostly open, but visitors centers, restaurants, and vending machine areas are closed.
2. Superchargers at fast food restaurants are problematic. They are open for takeout only and restrooms are closed. See #1... don't pass up a good rest stop bathroom.
3. Convenience store SCs like Wawa and Sheetz were fine. All were open because they sell gas.
4. All the SCs I used at hotels had open bathrooms. None of the hotels were closed.
5. I had gloves and hand sanitizer and used them at every SC.
Hope this helps.