I bet once you have the MPP comforts installed, you and your wife aren't going to feel the need to change wheels/tires.
The MPP's solve the harshness of hitting unevenness in the road more than any tire change, and they also solve the way the Model 3 lifts you up and forward in your seat when you go over uneven pavement at freeway speeds. That's a really annoying and uncomfortable feeling that should have been dialed out of the suspension by Tesla. No tire change is going to fix that, but the MPP's will. They did for me.