I have a Ford F-150 switched from stock tires 265/70R 17 to the same size in Toyo open country M/T 10ply/load E very aggressive deep tread. I lost 3 MPG, 22MPG to 19MPG at 70 MPH. A loss of 13.63 percent. The physics of rolling resistance, (see Mitchlen Tire "tools" Rolling resistance comparison). Increase tread depth, tire size, load rating, Load, all increase rolling resistance.
Add my tools, 95 gal diesel fuel tank for tractors. Now at load capacity around 7500lbs. MPG is down to 15MPG at 70 MPH a 31.81% loss.
I believe the Tesla pickup will be much efficient than the Ford F-150. These are the numbers I have to compare. Tires are Tires.