Daniel in SD
(supervised)
Thanks, wasn't too bad. Very tired and achy for a few days with low level fever.
I assume one these "flirt" variants are what got me (right at the yearly low point for circulation!).
-
Want to remove ads? Register an account and login to see fewer ads, and become a Supporting Member to remove almost all ads.
Coronavirus
- Thread starter Wenche
- Start date
I assume one these "flirt" variants are what got me (right at the yearly low point for circulation!).
AlanSubie4Life
Efficiency Obsessed Member
I wonder how many NoVIDs are left?Just got Covid for the first time last week so 0% effective as far as I'm concerned.
Last year they presented a bunch of data on the previous vaccine when they were approving the new one.
Still being overly careful and weird about my COVID prevention strategies. Life more or less fully back to normal though. Other than the strategic masking. And mostly avoiding eating indoors. Though getting more lax with that. It does seem that generally it requires somewhat prolonged contact, a certain dose. A few virus vigorously inhaled may not be an issue.
Still haven’t got it.
Hoping to get to 10 vaccines before I succumb. I’m at 7, so I can get there by September 2025.
Last edited:
COVID is ubiquitous now. It's become as common as the common cold. There are very few people who haven't had at least one variant at this point.
I'm glad you got a mild case, though that is the norm these days.
I have a friend who is immune compromised and has asthma from SARS back in 2002 (she caught it on a flight cross country). Her husband is not careful, he went to a casino, got COVID and gave it to her. She was sick with a fever for a couple of weeks. He has type II diabetes and was a heavy smoker for many years. He has terrible circulation and needed surgery on his leg to try and get circulation going again. They had to do the surgery while he was sick. Afterwards he developed pneumonia. The surgery was only partially successful and he may lose the leg, which will require he go into a nursing home.
Most of the people who get seriously ill with COVID now are people who have other health problems.
dhanson865
Well-Known Member
as far as I know my wife and I are still NoVids.
I've had 3 vaccines in 2021, 2 vaccines in 2022, 1 vaccine in 2023.
I haven't gotten a 2024 vaccine yet.
I'm only using the masks to mow the lawn now. But I'm ready to mask up if things get bad again.
Boosted just prior to 2.5 weeks of planes, trains, restaurants, crowds, 6 countries. I wore a mask for a few hours on the way out. My wife was better about it. Nothing, and we're home...still never evers.
AlanSubie4Life
Efficiency Obsessed Member
I suspect NoVIDs are overrepresented in following this thread!
A great thing about my used masks is that I have an enormous pile of used N95s which I can use for yardwork, using the leaf blower, etc., which is a game changer. So nice to block all that stuff and not be removing it from my nose for the next couple days. Inhaling brake dust, tire dust, etc., really can't be good for you anyway, when blowing the driveway or sidewalks.
Last edited:
Last year I had to use an air gun to paint a shed. I broke out the N95s left over which saved wear and tear on my lungs.
I do wonder if I had a subclinical case or two somewhere along the line. They aren't uncommon. I have to have been exposed often enough. And as far as immunity, what doesn't kill you or give you long covid makes you stronger.
I didn't intentionally leave my mask in the hotel storage while we bicycle toured, but I did. The rest of our group wore masks in tight places, and I would have as well.
I find them great for sanding redwood and grinding and other projects.
Estimates about six months ago were that ~ 35-40% of ppl with a primary covid infection were sub clinical or asymptomatic, so they ‘thought’ they had never been infected, regardless of exposure. Interestingly, some of the largest impacted patients with long covid reported that they did not THINK they had been infected. Large population sampling in the USA and UK, indicated ~ 85%+ of populations in UK/US had had at least ONE primary infection. Younger demographics (under 15) were higher in the 90% confidence ranges and individual reporting of that group showed the majority with 2+ infections.
Today, if you’re interested or concerned (possible long covid symptoms, at risk population, etc.) An IGg Nucleocapsid antibody test will confirm prior NATURAL infection, differentiating between antibodies created by natural infection vs. vaccination. It’s POSSIBLE that if it was so long ago, like early 2020 that one could show no antibodies, but really not probable. The Igg tests are designed to show this. Most ppl will still show Igg antibodies for things like Epstein Barr, even though infection was decades ago. (Nearly 95% of populations having been exposed)
Having reached a near term low of circulating virus in May 2024, back to levels from last July 2023, or June 2022, we’re in an uptrend. It’s uncertain how much it will increase in the summer months. With only ~ 20% of western populations having had ANY inoculation in the past 9 months, chances are high that we’ll see infections increase for the summer. I just had a friend get sick on a Mediterranean cruise. Oddly, they quarantened her in her cabin for five days. But it was a super luxury yacht with ~ 50 passengers..maybe they were worried about a further outbreak.
And another remote family member who just sadly had her 7th infection. She was already struggling with post covid/long covid issues and will probably only get worse at this point. Lasting neurological and pulmonary issues being the biggest, with cardiological a close third.
It’s gone pretty unnoticed but $MRNA is up ~ 40% in the past three months. Novavax making deals for combo updated covid and flu boosters.
It IS a positive that more recent variants do seem to be lower virality and impact. That was what I was always hoping for. but, I’ll always be wearing a good fitting N95+ mask during air travel at least.
This ain’t over yet.
Generally agree, but I'm not sure I followed your statement here. If we hit a low this month, how can we know we're on an upturn now? It's still May. Reports aren't complete.
Anyway, I totally agree that most, but not all, have had natural exposure, if not disease. I can't help but think that it's better to have exposure without disease. Most studied cases of long COVID follow severe, at least hospitalization, requiring cases. Granted, we don't know everything.
Yeah, a mask is a good idea on a flight especially if you have someone sitting behind you coughing the whole time, not wearing a mask. As we did.
Incidentally, we qualified for the spring boosters, so we had them 2 weeks before we left to sort of maximize antibodies during the trip.
Last edited:
Yes, it was really late April early May data that put us at the prior LOW, but now upticking.. data comes out bi-weekly, mostly bio-bot waste water data (which is NOT perfectly understood) and reported confirmed cases, which is POOR and underreported at this point.
About 1/3 of long covid sufferers, symptomatic and now clinically tested reported ‘thinking’ they had NO prior infection. With the symptoms they currently have, they are either presumed covid, or tested for Igg NCSP antibodies. So yes, hospitalization, intubation, those that required longer duration supplemental oxygenation those things ultimately lead to more lasting clinical impairment if not necessarily long covid. Lasting impairment for that group is more on pulmonary impact, cardiac impact, neurological impact (5-10% reduction in tested IQ, executive decision making, problem solving)
I was speaking with a dr./phd immunologist friend of mine late last year and he said at that point, he’d rather have HIV than a lasting impairment covid infection.
Update: the post above should read:
Having reached a near term low of circulating virus in May 2024, back to levels from last July 2023, or Feb 2022
Last edited:
Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses | Washington University School of Medicine in St. Louis
Response to updated vaccine is shaped by earlier vaccines yet generates broadly neutralizing antibodies
medicine.wustl.edu
"...some scientists worry that the remarkable success of the first COVID-19 vaccines may work against updated versions, undermining the utility of an annual vaccination program. A similar problem plagues the annual flu vaccine campaign; immunity elicited by one year’s flu shots can interfere with immune responses in subsequent years, reducing the vaccines’ effectiveness.
A new study by researchers at Washington University School of Medicine in St. Louis helps to address this question. Unlike immunity to influenza virus, prior immunity to SARS-CoV-2, the virus that causes COVID-19, doesn’t inhibit later vaccine responses. Rather, it promotes the development of broadly inhibitory antibodies, the researchers report.
..."
--------------
Don't see any mention of differences between vaccine- and infection-acquired immunity.
I know I've had a couple of more or less sub-clinical infections. Over the last 4 years I've had the feeling I was coming down with something, got a good night's sleep and was fine the next day. Three times I did anti-body tests within a couple of weeks of that and every time my anti-body count was very high. The closer I tested to when I felt off, the higher the anti-body count.
I am sure now I had original COVID, but wasn't sure for about 4 months when information started coming out about the lost of taste and smell. I had that for about 4-6 days and had what seemed like an asthma episode that wouldn't go away for about three weeks. No other symptoms except felt like I was coming down with something the last day. I got up, felt a little feverish, went back to bed and slept until 4 PM and felt fine. All symptoms gone. My partner got sick with something low grade that lasted about 4 days just after that and she has long COVID now.
AlanSubie4Life
Efficiency Obsessed Member
Yeah, seems like a non-issue.Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses | Washington University School of Medicine in St. Louis
Response to updated vaccine is shaped by earlier vaccines yet generates broadly neutralizing antibodies
"...some scientists worry that the remarkable success of the first COVID-19 vaccines may work against updated versions, undermining the utility of an annual vaccination program. A similar problem plagues the annual flu vaccine campaign; immunity elicited by one year’s flu shots can interfere with immune responses in subsequent years, reducing the vaccines’ effectiveness.
A new study by researchers at Washington University School of Medicine in St. Louis helps to address this question. Unlike immunity to influenza virus, prior immunity to SARS-CoV-2, the virus that causes COVID-19, doesn’t inhibit later vaccine responses. Rather, it promotes the development of broadly inhibitory antibodies, the researchers report.
..."
--------------
Don't see any mention of differences between vaccine- and infection-acquired immunity.
I wish they would double the cost and recommend a two-shot series of boosters in future, just to see whether it helps significantly with efficacy. Also, pick the right darn candidate for the virus. Hopefully they'll pick Flirt or whatever this year, but even that is probably not correct. They need to take a guess on the most fit successor to Flirt if it shows up in the next week. It seems like there is a decent understanding these days of what the most likely fittest one will likely be, once there is any sign of it, but unfortunately it seems the "science" requires better firmer data on that (meaning it is actually showing signs of fitness, not just theoretically fit) before the vaccine board will actually recommend that variant be used for the vaccine candidate. Sad!
Or we can hope it's mostly done evolving and has run out of space.
Right. They just looked at antibody response to vaccine.Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses | Washington University School of Medicine in St. Louis
Response to updated vaccine is shaped by earlier vaccines yet generates broadly neutralizing antibodies
"...some scientists worry that the remarkable success of the first COVID-19 vaccines may work against updated versions, undermining the utility of an annual vaccination program. A similar problem plagues the annual flu vaccine campaign; immunity elicited by one year’s flu shots can interfere with immune responses in subsequent years, reducing the vaccines’ effectiveness.
A new study by researchers at Washington University School of Medicine in St. Louis helps to address this question. Unlike immunity to influenza virus, prior immunity to SARS-CoV-2, the virus that causes COVID-19, doesn’t inhibit later vaccine responses. Rather, it promotes the development of broadly inhibitory antibodies, the researchers report.
..."
--------------
Don't see any mention of differences between vaccine- and infection-acquired immunity.
The good thing is that boosters broaden rather than block antibody response to variants, and such that boosters may actually cover as yet to develop variants. Which means picking a specific variant for the next booster is less important than it would be with influenza.
I could only see the original article in Abstract. It hasn't been edited yet: it's in prepublication release. There may be interesting details yet to come.
AlanSubie4Life
Efficiency Obsessed Member
Unfortunately does not seem to be resulting in effective infection blocking. They should just try a double booster strategy and compare efficacy.
They do do that for people of high risk. 2 month series booster. And it does help.
Should You Get an Additional COVID-19 Bivalent Booster?
A Yale Medicine specialist answers questions about an additional COVID-19 vaccine bivalent booster dose for people who are 65 and older or immunocompromised.
www.yalemedicine.org
Similar threads
