No major differences on the main page - missing the zoom buttons and secondary streets are harder to see.
The major change in the app launcher. The infamous defogger/defroster and seat warmers are moved to the HVAC submenu. If there is a passenger they will receive their own temp control, regardless if the control is split or not.
You have the ability to put up to 4 apps (toolbox, theater, camera, various streaming sources) and there is the last used app. As for the apps, it is clear that they were optimized for horizontal screen - for example, the podcasts lists are horizontal now (which cuts some of the topics). The browser is not full screen anymore.
There are many reviews on YT - just search for Tesla V11.