Launching at a different time would require an "orbital phase maneuver" to synchronize the orbits once in space, which would add complexity, time, and risk. I'm not sure Dragon is designed to stay attached to the second stage after launch, but for a significant orbital shift they would have to launch into an elliptical orbit with a different period from the ISS, wait until they are synchronized with the plane of the ISS, then fire the second stage again to match the ISS' circular orbit. Dragon has limited life support capability (only a day or two?), and its own thrusters, even Super Dracos, are only capable of a very slight phase shift over that amount of time. (Anyone want to calculate how much?)