It's very easy as there as so many superchargers along that route.
The in-car routing ususally does a pretty good job, but don't hesitate to second-guess its choices. For example on one occasion it picked up a super slow 72kW Urban Supercharger while there was a 250 kW v3 just two blocks away. Or also a couple of times it needlessly slow-charged beyond 90% to skip the next charge stop, but when I added it to my route my time to destination immediately dropped by 15 minutes. So it does not always make the best choices, and ABRP is also a good idea to have as an app on your cell to see if that's the case.
Cost of supercharging is similar than in Canada, during my trip to North Carolina last week, I averaged 86$CAD per 1000 km.
Don't forget to bring some cash in USD for some tolls that only accept that form of payment (or else you get a traffic violation ticket). I think that was a handful of tolls in Delaware or New Jersey, I forgot. Otherwise it's credit cards or pay by mail later (license plate photos) like most of New York State. If you are planning to do this on a regular basis you may consider getting an E-ZPass.