One thing your wife would benefit from is using the "Energy" display on the MCU to show the "Projected Range" based on the average energy consumption in real-time and the anticipated elevation climb/decent as well as traffic conditions. It lets you know when perhaps you need to keep the speed down to lower your rate of fuel consumption.
A more practical suggestion that builds on the notion of the Energy display, but is much easier and may pass the WAF (wife acceptance factor), is to have your wife set the Navigation routing on her way home each afternoon. It's not about the routing itself of course, rather, the car will advise both at the start of the trip, as well as during the trip, with realtime calculations when one needs to slow down, and by how much, to get home reliably and with a margin of error. And if the margin gets too small, I believe it will re-route you to a charger as a waypoint.
Example, yesterday left the house on a 90-mile roundtrip excursion, with less than 50% battery on my S. On the way there, the navigation estimated returning to starting point (home) would end up with about 4% battery. As we started on the way home, it still projected 4% at home, and cautioned to keep speed below 65 mph to make it. During the 45-mile freeway drive, I stayed around 70 initially, and with a slight detour the projection dropped to 3%, the warning stayed on screen. But after a few minutes the flow of traffic dropped to 60 mph, the estimate increased to 5%, and later when going at 70 mph, the warning went away. So the car is constantly updating its projection based on realtime consumption, and the route remaining, and will tell you how much to drop speed. (BTW, there was never any range concern as I had multiple superchargers along my route..)
25 to 50 miles remaining is a lot though, so this may not initially alleviate any anxiety because your wife will never see these warnings until it projects less than 5%, which is going to be closer to <18 miles remaining. Once you get to experience these realtime warnings though, it becomes really clear how much the car is looking out for you and will keep you from being stranded - and thus give you confidence you don't need to worry so much if you don't see the warnings.... but to do so it does need to know where you're going...