BerTx: Would you go via Dallas-OKC-Amarillo-Albuquerque and then cut south? My concern on this particular route is winds around Amarillo and how that might effect range.
Winds are definitely a factor to watch wherever you travel! There are prevailing, strong westerly winds in the Fort Stockton area as well, so it is tough to avoid them completely whatever route you take.
I would go the direct route through I-10 all the way. I would plan for a meal stop in Columbus and charge as much as possible while eating at the Mexican restaurant there, then stop again to top up to 95% in Flatonia. Then go to Junction and Ozona, charging to 100% in Ozona. Your problem here is that the winds often pick up in the afternoon, so you will need to be very careful and likely drive slowly (start off at 60 mph and speed up if it looks like you will have enough range) for this stretch. You do have a couple of places to charge in a pinch (Ft Stockton RV park and Balmorhea city RV park) but planning to use those will be much slower than simply slowing down. Some people think diverting to Iraan and charging there helps, but in my experience with my 48A charger it is not worth the extra miles and elevation change.
Driving at a slow speed on I-10 seems unsafe to someone from Houston, but this is not the same I-10 as you are used to. The trucks are mostly going 70-75 mph, and there just is not much traffic. You won't be clogging things up very much.
BUT, I'd watch the weather forecast very closely and not set myself up to have to be somewhere at a particular time. If the wind is blowing strongly from the west, your progress will be very much slower.
If you don't want to worry about things, the route that
@TexasEV recommends is much better, definitely cutting from Cisco or Sweetwater up to Childress and Amarillo. No need to go through OKC at all.