Ok, it looks like we’re done with covid and on to philosophy and other esoteric topics. I’m done. Bye.
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Coronavirus
- Thread starter Wenche
- Start date
Geisinger requiring vaccination for transplant recipients
A woman in Lycoming County was notified last week that she will not be eligible for a kidney transplant because she refuses to get vaccinated for COVID-19.
She says she wants to find out the long term effects of the COVID vaccinations. This from someone who is in need of a kidney transplant.
A woman in Lycoming County was notified last week that she will not be eligible for a kidney transplant because she refuses to get vaccinated for COVID-19.
She says she wants to find out the long term effects of the COVID vaccinations. This from someone who is in need of a kidney transplant.
AlanSubie4Life
Efficiency Obsessed Member
Hopefully Trevor is not right, but he usually is! I’m hoping for less antigenic drift in the endemic state.
TLDR: expects 40k-100k deaths a year (similar to influenza) on an ongoing basis in the US. Some of us vaccinated here will presumably die of COVID eventually in future years (though it will be uncommon) if things transpire that way.
TLDR: expects 40k-100k deaths a year (similar to influenza) on an ongoing basis in the US. Some of us vaccinated here will presumably die of COVID eventually in future years (though it will be uncommon) if things transpire that way.
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FlatSix911
Porsche 918 Hybrid
Isn't it true that over 4-5 Million deaths were caused as a result of the virus that originated in Wuhan City, Hubei Province, China? The truth.
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Well that is a non sequitur. Completely ignores my questions. But let's run with it. How many deaths would there be if everyone was vaccinated? Because when you want to talk about "causation" at some point your "cause" will become too remote to be a legal cause. I would argue today - for anyone in the united States the legal cause of death from COVID is most likely going to be their failure to get vaccinated. You have a duty to mitigate damages. If someone throws a ball through your window you cannot simply stand by and watch the rain come in and ruin all your furniture. You have a DUTY to stop the damage. Today you can easily, in the United States, stop the damage of COVID by simply getting a free vaccination.
U.S. FDA staff says Moderna did not meet all criteria for COVID-19 boosters
"Scientists at the U.S. Food and Drug Administration said on Tuesday that Moderna Inc (MRNA.O) had not met all of the agency's criteria to support use of booster doses of its COVID-19 vaccine, possibly because the efficacy of the shot's first two doses has remained strong.
FDA staff said in documents that data for Moderna's vaccine showed that a booster does increase protective antibodies, but the difference in antibody levels before and after the shot was not wide enough, particularly in those whose levels had remained high."
"Scientists at the U.S. Food and Drug Administration said on Tuesday that Moderna Inc (MRNA.O) had not met all of the agency's criteria to support use of booster doses of its COVID-19 vaccine, possibly because the efficacy of the shot's first two doses has remained strong.
FDA staff said in documents that data for Moderna's vaccine showed that a booster does increase protective antibodies, but the difference in antibody levels before and after the shot was not wide enough, particularly in those whose levels had remained high."
Merck Asks FDA to Approve First COVID-19 Antiviral Pill
Experts say authorization of molnupiravir, at this time only for use in high-risk Americans, could be a major advance in the struggle against COVID-19 because a convenient, more affordable treatment could reach many more high-risk patients than the more complicated monoclonal antibody treatments now used, according to The New York Times.
AlanSubie4Life
Efficiency Obsessed Member
This seems short sighted, and hopefully they will recommend boosters for over 65, as for the other vaccine. Lots of meetings coming up over the next week. NIH data on mix-and-match vaccines coming too.
Article
A study of COVID vaccine boosters suggests Moderna or Pfizer works best
on a small study by the NIH
https://www.medrxiv.org/content/10.1101/2021.10.10.21264827v1.full.pdf
"If you got the Johnson & Johnson vaccine as your first COVID-19 shot, a booster dose of either the Moderna or Pfizer-BioNTech vaccine apparently could produce a stronger immune response than a second dose of J&J's vaccine. That's the finding of a highly anticipated study released Wednesday.
And if you started out with either Pfizer or Moderna, it probably doesn't matter that much, the research suggests, as long as you get one of the two mRNA vaccines as a booster."
A study of COVID vaccine boosters suggests Moderna or Pfizer works best
on a small study by the NIH
https://www.medrxiv.org/content/10.1101/2021.10.10.21264827v1.full.pdf
"If you got the Johnson & Johnson vaccine as your first COVID-19 shot, a booster dose of either the Moderna or Pfizer-BioNTech vaccine apparently could produce a stronger immune response than a second dose of J&J's vaccine. That's the finding of a highly anticipated study released Wednesday.
And if you started out with either Pfizer or Moderna, it probably doesn't matter that much, the research suggests, as long as you get one of the two mRNA vaccines as a booster."
COVID-19 continues to be a leading cause of death in the U.S. in September 2021 - Peterson-KFF Health System Tracker
"This brief revisits where deaths from COVID-19 rank among leading causes of death in the U.S.
We find that COVID-19 was the second leading cause of death in September 2021.
We also find in September COVID-19 was the number 1 cause of death for people age 35-54 and among the top 7 leading causes of death for people in other age groups.
We also estimate how many COVID-19 deaths were among unvaccinated adults and could have been prevented since June 2021 when safe and effective COVID-19 vaccines became widely available to all adults in the U.S.
From June through September 2021, approximately 90,000 COVID-19 deaths among adults likely would have been prevented with vaccination."
"This brief revisits where deaths from COVID-19 rank among leading causes of death in the U.S.
We find that COVID-19 was the second leading cause of death in September 2021.
We also find in September COVID-19 was the number 1 cause of death for people age 35-54 and among the top 7 leading causes of death for people in other age groups.
We also estimate how many COVID-19 deaths were among unvaccinated adults and could have been prevented since June 2021 when safe and effective COVID-19 vaccines became widely available to all adults in the U.S.
From June through September 2021, approximately 90,000 COVID-19 deaths among adults likely would have been prevented with vaccination."
dhanson865
Well-Known Member
COVID-19 may have caused the extinction of influenza lineage B/Yamagata which has not been seen from April 2020 to August 2021
www.nature.com
Influenza lineage extinction during the COVID-19 pandemic? - Nature Reviews Microbiology
The SARS-CoV-2 pandemic has seen a notable global reduction in influenza cases of both influenza A and B viruses. In particular, the B/Yamagata lineage has not been isolated from April 2020 to August 2021, suggesting that this influenza lineage may have become extinct, which may provide...
www.nature.com
Nature article on immunity from having had COVID. According to this research having had it gives you better immunity than the vaccine.
COVID super-immunity: one of the pandemic’s great puzzles
However it doesn't address the downsides of having had COVID. Even among those who don't have bad cases, long COVID is proving to be more and more common.
My partner started a course of low dose naltrexone for long COVID. It's shown to help with the symptoms, but nobody knows if this will be required for the rest of her life or just for a while. She's only two weeks into titrating up the dose (1/2 mg increase a week) and she's feeling like she has more energy than she has in a year and a half.
COVID super-immunity: one of the pandemic’s great puzzles
However it doesn't address the downsides of having had COVID. Even among those who don't have bad cases, long COVID is proving to be more and more common.
My partner started a course of low dose naltrexone for long COVID. It's shown to help with the symptoms, but nobody knows if this will be required for the rest of her life or just for a while. She's only two weeks into titrating up the dose (1/2 mg increase a week) and she's feeling like she has more energy than she has in a year and a half.
From what I can see they only compare hybrid immunity (infected then vaxed) to a full course of vaccination !?
Not infection alone !?
JRP3
Hyperactive Member
This part was interesting regarding longer intervals between doses:
EVNow
Well-Known Member
I thought earlier in the article it talked about immunity from just having the virus.
Well I would be interested in hybrid - fully vaccinated and then infected. MY wife got COVID 5 months after being fully vaccinated.
An article
Immune Responses From 3 Different COVID-19 Vaccines Compared Over 8 Months
on this paper
https://www.nejm.org/doi/full/10.1056/NEJMc2115596
"In a paper published in the New England Journal of Medicine, a team of experts at Beth Israel Deaconess Medical Center (BIDMC) compared immune responses induced by the three vaccines over an eight-month follow-up period. The investigators evaluated the 61 participants’ levels of various antibodies, T cells, and other immune products at two to four weeks following complete immunization – the time of peak immunity – to eight months after vaccination.
...
“The mRNA vaccines were characterized by high peak antibody responses that declined sharply by month six and declined further by month eight,”
...
“The single-shot Ad26 vaccine induced lower initial antibody responses, but these responses were generally stable over time with minimal to no evidence of decline.”
The team also found that mRNA-1273 elicited antibody responses which were generally higher and more durable than BNT162b2. All three vaccines demonstrated broad cross-reactivity to variants of SARS-CoV-2, the virus that causes COVID-19. The findings have important implications for understanding how vaccine immunity may wane over time; however, the precise immune responses necessary to confer protection against SARS-CoV-2 has not yet been determined, the researchers point out."
Immune Responses From 3 Different COVID-19 Vaccines Compared Over 8 Months
on this paper
https://www.nejm.org/doi/full/10.1056/NEJMc2115596
"In a paper published in the New England Journal of Medicine, a team of experts at Beth Israel Deaconess Medical Center (BIDMC) compared immune responses induced by the three vaccines over an eight-month follow-up period. The investigators evaluated the 61 participants’ levels of various antibodies, T cells, and other immune products at two to four weeks following complete immunization – the time of peak immunity – to eight months after vaccination.
...
“The mRNA vaccines were characterized by high peak antibody responses that declined sharply by month six and declined further by month eight,”
...
“The single-shot Ad26 vaccine induced lower initial antibody responses, but these responses were generally stable over time with minimal to no evidence of decline.”
The team also found that mRNA-1273 elicited antibody responses which were generally higher and more durable than BNT162b2. All three vaccines demonstrated broad cross-reactivity to variants of SARS-CoV-2, the virus that causes COVID-19. The findings have important implications for understanding how vaccine immunity may wane over time; however, the precise immune responses necessary to confer protection against SARS-CoV-2 has not yet been determined, the researchers point out."
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