Anecdotal experience:
Not long after I got my model S we had a rather strong thunderstorm pass by overnight while the car was charging. There was a big lightning strike very close by that caused a power surge and momentary outage.
Right after it happened I could hear my car in the garage, cooling fans going absolutely crazy, running at full tilt. Stayed that way until I stopped charging, unplugged the UMC, and rebooted the MCU.
No apparent damage or long term impacts, but since that event I make an effort to unplug the car in weather like that if I can.