Range would take a blow with the current pack sizes. Charge rates (mph/kph) would also take a hit. And top speed. And if it's actual armour to the point of upping the weight, you're looking at more tire wear, worse handling, worse acceleration, even more efficiency losses (see above), etc. And all reduction of efficiency means more cycles put on the pack.
Cybertruck is a consequence of the parameters it was optimized for - "taking abuse, going anywhere, and being able to do huge feats of strength". Not "getting around quickly and efficiently".
I know everyone is really excited about the new cybertruck design language, and it is awesome, but I need to remind people, the laws of physics haven't changed. Tesla has done an admirable job trying to make the vehicle efficient despite its shape... but I'm sure I'm not the only one who noticed that this is the first vehicle they've ever unveiled where they haven't bragged about the drag coefficient.
ED: All this said... while basic car shapes (including curvature in key places) are not up for negotiation as far as efficiency goes, the specific details in many locations can be, and there's many places Tesla could go for a more angular design language without meaningful adverse consequences. If this new angular design language really does take off, I wonder if we might get a sort of hybrid "smooth X angular" design language. Cybertruck's design language would AFAIK be classified as "brutalism" (stark, low-contrast shading; functional geometric shapes without flourishes, etc), so maybe we might transition to a sort of "post-brutalism" design language.
Airflow-aligned features tend to have relatively limited impact, particularly if the angle is low (such as style lines). Anything behind a transparent cover can take any design language (lights, for example). The rear end, after flow separation, has a lot of design language freedom, so you could transition from a smooth front end to a more polygonal rear end (so long as the cross section after flow separation is low), which I think might look really keen. Etc.