There is a difference here though. The compressed music is actually "less" sound than uncompressed. Chopping off bits here and there to save space because they are not going to be reproduced by most systems anyway is a true defined change to the original music. To tell the difference you MUST use a system capable of resolving the missing bits, otherwise it will sound exactly the same. These systems are available, and there are quantifiable and objective ways to measure the differences.
If you fire up a standard bose stereo set and try to hear the differences between the uncompressed and compressed, you are going to say they are exactly the same. Try the same thing with a properly setup studio system in a nice quiet room, or a high end pair of headphones... The differences should be obvious.
Electricity, on the other hand, doesn't really care about the wires being used. Especially at the low amounts of power for firing up speakers. If you change the electrical properties of the wires (introduce things that could be pseudo capacitors, increase resistance, for example) then there would be a change to the resulting sound away from the original intent. Using wires, no matter the type/source, as long as they are at least "just big enough" and are not picking up outside signals will work just fine. I've never seen a reliable objective test on wires that proved they affect anything.
(This isn't true on analog signal cables though, they are significantly lower in power and can pick up outside signals or have dropoff or any number of other things which get picked up and magnified, but that's another show.)