I used to be confused by various things GOP politicians did too.
But everything is explained by one thing - what motivates GOP base is the culture war. Anything and everything can be made part of the culture war by the politicians / media - and the base will follow. There is no particular reason to politicize masks or vaccines. But they align quite well with the culture war narrative - so were made part of it by the politicians.
DeSantis is planning a run for President in 2024 (if Trump doesn't run). So, expect him to be at the forefront of such efforts.
Well, we can all agree that they are definitely willing to die for their beliefs. This helps thin the herd and ensure they are not the majority. LOL