TOU = "time of use" which, in this context at least, is talking about electric utility billing plans that bill you different rates for when you use your power, as well as how much you use. In a Time of Use plan, electricity is cheaper (usually) in the middle of the night.. much cheaper, in exchange for a "peak" time charge in the late afternoon to evening, from 4-9 or 5-9 that is triple (or more) the nighttime rate.
NEMA 14-50 = 50 Amp electrical outlet, of a specific type. This is an electrical outlet that you would plug "a charger" into. Many people get an electrician to put in (or put in themselves) this outlet, then plug in the connecter that comes with the car into it, and use that to charge. You dont need a NEMA 14-50 outlet because you already have the chargepoint.
There are other NEMA plugs but for car charging, the 14-50 is the one many people like to talk about here.