In relation to this topic, that's an extremely silly response as the controls in your vehicle are not going to up and move 12 inches to the right while you're sitting in the driver seat.
As far as the keyboard, have you really never noticed these handy bumps on the F and J keys that provide tactile feedback? They let you orient yourself without having to look at the keyboard. Even without those, just find the left end of that big, long, space bar then move up to the C, diagonally up to the D, and
Bob's your uncle.
In a vehicle the buttons & knobs tend to have rather distinct shapes, making it that much easier to orient yourself without looking.
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