I think not only the amount of G-force, but the duration is a factor too.
At the extremes, "high-G" can disrupt breathing and blood flow.
As long as you don't panic and go into shock, you could probably handle this for many seconds before your cells start to run short of energy.
For most applications... drag bike... roller coaster... plaid Tesla... The duration would be fairly short and probably not enough to get you into trouble.
But we also compare high-G for pilots and astronauts. Fighter planes need to make sure not to exceed G-levels that would "black out" a pilot in a long "dogfight". Those pilots may have special suits, or even take special drugs to compensate to give them an advantage.
Rockets carrying people need to be designed not to exceed the prolonged G's astronauts can handle.
I think rockets that won't carry people can be designed to accelerate more quickly.