I finally got around to installing my 18" TSportLine Tires/Wheels shod with 245/50 Michelin Pilot Sports All Season tires on my PMY. It's like a different vehicle. For the average driver that doesn't track their vehicles, I believe Tesla should offer this as the base tire/wheel, the 21s could be optional.
Aside from the obvious improvements in ride and comfort I no longer fear potholes or curbs and I can tell after 150 miles they are more efficient. And while I haven't tested performance with my DRAGY yet, I did do one 0 to 60 blast and can confirm the 245's grip is as good as the 21s, the car just went, with no fuss or drama. Expecting even better 0 to 60 times as a bonus.
And personally, I've never warmed to the uber low profile tire look that seems to be the rage these days. So for my money, this is the best setup for daily use. I live in IL and our potholes have zip codes and the roads in general suck.