I'll add my 2c. I live in Calgary and drive to Vancouver two or three times a year, which is just shy of 1000 km from home to destination. With an ICE, it would theoretically take about 10.5 hours, but factor in lunch and bathroom breaks and it's closer to 12 hours. At about 9 hours of driving, I would hit a mental brick wall and not be able to pay attention to driving, so I would have to stop for the night. I've never made it all the way in one go. Yet, with my Model S, I have had no problem doing it in one go. I hit every supercharger stop and in less time than it takes for my kids to go to the bathroom and get back in the car, my Model S is ready to go. We literally NEVER wait for the car. And it takes about 12 hours to get to Vancouver, but when I arrive, I still have energy. I guess it's akin to pacing yourself in a marathon (Model S) vs sprinting off the line (ICE).
So from personal experience, I'll say that I can do more driving with the Model S -- the supercharger breaks actually result in more driving in a day -- go figure!