Yes, for long road trips (requiring a charging stop), driving in an EV will take longer than driving in an ICE because an EV may need to stop more frequently for refueling and those stops will be longer.
However...
With an X LR+, even at 80 MPH, it should be possible to drive 2 hours without having to make a charging stop. So saying a 2 hour drive requires a 45 minute charging stop isn't reasonable.
With our 2018 X 100D, rated range is around 300 miles. If we charge to 100% before we leave home, we're able to drive 210 miles before we stop for supercharging, with about half of that drive at 80 MPH, getting to the supercharger with 5-15% of charge (depending upon conditions).
The Tesla navigation app can help considerably in managing charging stops. When we drive from Houston to Dallas, we'll enter our final destination and the navigation software will provide advice on how long we should stay at the supercharger to make it to our destination. We don't need to stay there for 45 minutes and get back to an 80-100% charge, since we'll need to drive less than 100 miles after the supercharging stop.
If you can start with enough charge to get to the destination without a charging stop, then an EV is the same as an ICE. If you need to stop once, the drive will be a little bit longer due to the charging stop. For very long trips requiring multiple charging stops (where you'll likely need to stay until you get to 80-90% charge), then the charging time will become a larger factor.
Though... We've found the extra rest time while charging has made the long drives easier. Stopping about every 3 hours for 30-40 minutes provides time to hit the restroom, get a snack/meal, check e-mail, play a game, ... Plus, if you can plan the stops when it's time to get a meal, the charging time will likely take about the same time it takes to get the meal.
As Tesla increases range (close to 400 miles of rated range for S) and more V3 superchargers are deployed, the impact of charging will become less in the next few years.