Sure. I am now working on using the buttons with my right hand when the wheel is turned upside down.Do you not have roundabouts and parallel parking in Germany?
I can already do it after driving the Highland for almost a week. It still takes me a second to make sure, but it seems obvious that in another week I will operate the buttons blindly with either hand, no matter how the wheel is turned.
The human brain is good at such things. It just needs a little time to take it in. No reason to worry. Everybody will learn it after a couple of weeks at most. You have to keep doing it, however. Initially you have to force yourself. It was the same after the indicator stalk had been invented.