I don’t see a 4680 Model S in the near future. With the (~500k) orders of the Cybertruck, the Semi, the Y and Roadster all needing these cells, I think it’s safe to say that the S will not be high on the priority list for these batteries. The S is definitely quite good as is.
When the new cells fly off the assembly lines and all other models have ramped up their production, the S will be due for an update anyway. I don’t expect a 4680 MS for at least 4-5 years. I may be wrong, but I’ve learned to lower my expectations real low with Elon’s promises.