I've said it before, I'll say it again: I like the design, and it doesn't look like a weird mobile. I test drove a Prius with the center speedometer, and it's fine and the speed was actually more visible at all times because it was higher up than my Volt's dash screen behind the steering wheel and in my peripheral vision. The Model 3 screen looks like it's placed so the top of the screen is about even with the bottom of the windshield from the viewpoint of the driver, so it should be the same (but of course I won't know for sure until I sit in it myself). The key will be the UI. If it's done well and utilizes those balls/scroll wheels/whatever they are in the steering wheel properly, it could be better than fiddling with buttons. Changing radio stations and flipping through different information screens on my Volt infotainment screen is great and a little safer, imo, than doing so on my old Lexus with buttons because the infotainment screen is higher up and the road is in view for me at all times with my peripheral vision. A bad UI would make the whole thing a disaster, but I won't stress about it until I see it.
The single vent thing worries me a bit, because, as I've said before on this forum, I like directing air to my face and will be disappointed if I can't do so with the Model 3 vent. But if the new design reduces fan noise, then maybe a higher air speed will compensate, or maybe there will be a way to adjust the vent position anyway with the touch screen or a scroll wheel or just manually (I can't remember the last time I changed my vent positioning while driving, once I've set it I'm fine). I'll just have to wait to test drive it to make a decision.