Interestingly enough, my very first long trip with the Model S included Burlington -> Asheville and back.
Lots of pics and data in this post:
Southern NJ to Central NC, then Asheville, and back - Page 4
Weather was *terrible*. Was in the 30s or lower the whole time, in the middle of an ice storm. You couldn't even really walk safely in the parking lot at the Burlington supercharger.
Notably, here is my SoC graph for the trip:
DE = Newark, DE
VA = Glen Allen, VA
NC = Burlington, NC
FAM = My family destination in NC that is east of Asheville a ways (about 1/3rd of the way).
J1772 = 6kW Charger at a Mercedes dealership in Asheville
(the rise in SoC before the last FAM) = J1772 charger at the Energy United office in Statesville, NC
And here is my speed graph:
You can see I just took it pretty easy heading to Asheville and made it with plenty of charge to spare. I made it with 40% SoC, so even without the +15% I got at my family destination before heading back out I would have easily made it with 25% battery left. So, doable without a range charge in Burlington for sure.
Fortunately it warmed up substantially while my car was charging in Asheville, and that made the return trip a piece of cake (60s).
This was my very first long trip after buying the Model S, and it was probably some of the worst conditions possible. But it was done!