Do most truckers pull non-stop 11 hour runs, without a stop for bathroom or food? If so, that seems dangerous, and perhaps being forced to stop isn't a bad thing.
In the EU that would be illegal. The EU mandates a minimum of 45 minutes of breaks for every 4 1/2 hours driving. If Tesla can make it so that its semi can keep running indefinitely with 45 minutes of charging broken into one or two stops for that 4 1/2 hours of highway driving, then they have an immense advantage. Fueling costs are around 40% of the cost of running a rig. Amortizing the cab is under 20%. Then there's maintenance and everything else that they have the potential to save. If they can halve fueling costs without affecting throughput in the EU they could literally charge twice as much for their trucks and still make great sales.
I assume Tesla will start (like they do with everything) on the high end - a decked out super-comfortable sleeper cab with tons of power at the wheels. I bet it's going to be gorgeous inside.
Even in the US, without the rest requirements and much cheaper fuel, I can still see good sales. Small slowdowns to stop for supercharging would be acceptable because fueling costs so much (even at US prices); you could funnel the savings into additional trucks and drivers to make up for any lost time.